医生介绍
王琛,男,医学博士,硕士生导师。入选九院第五届优秀青年骨干、交大医学院优秀青年教师。师从资深整形外科专家钱云良教授和微整形专家王丹茹教授,主要工作涉及瘢痕修复、唇鼻再造、腹壁缺损修复和脂肪干细胞治疗等领域。独立承担包括国家自然科学基金在内的5项课题,参与“973”、“863”计划、国家自然科学基金面上项目以及上海市优秀学科带头人计划等多个项目的研究。近五年在Biomaterials、Tissue Eng、Am J Surg等刊物上发表SCI论文十余篇,其中部分文章作为Feature article发表。参与编写专著2部。临床上除了传承传统的修复手术之外,还对外伤后歪鼻畸形、鼻再造(亚单位再造)、小儿烧伤后颈部瘢痕挛缩的修复进行了一定的改进,并针对小儿的生长发育特点,初步提出了小儿颈部瘢痕挛缩的分类和治疗策略(序列治疗)并进一步完善鼻翼缺损、鼻再造分型和治疗策略,从而形成以大数据医学和精准医学为指导,以个性化的治疗方式使每个患者得到更好的治疗效果。在美容整形外科方面,在微整形专家王丹茹教授的指导下,根据求美者的要求,用个性化的方式,用最小创伤达到最理想的整形美容效果。
科研成果:
主要发表文章:
1. Wang C, Cen L, Yin S, Liu Q, Liu W, Cao Y, Cui L. A small diameter elastic blood vessel wall prepared under pulsatile conditions from polyglycolic acid mesh and smooth muscle cells differentiated from adipose-derived stem cells, Biomaterials, 2010,31(4):621-630.
2. Wang C, Yin S, Cen L, Liu Q, Liu W, Cao Y, Cui L. Differentiation of adipose derived stem cells into contractile smooth muscle cells induced by TGF-β1 and BMP4, Tissue Eng Part A, 2010,16(4):1201-1213.
3. Yin S, Cen L, Wang C, Zhao G, Sun J, Liu W, Cao Y, Cui L. Chondrogenic transdifferentiation of human dermal fibroblasts stimulated with cartilage derived morphogenetic protein1, Tissue Eng Part A,2010,16(5):1633-1643.
4. Wang C, Guo F, Zhou H, Zhang Y, Xiao Z, Cui L. Proteomic profiling of tissue-engineered blood vessel walls constructed by adipose-derived stem cells, Tissue Eng Part A, 2013, 19(3-4):415-425.
5. Wang X, Qian Y, Jin R, Wo Y, Chen J, Wang C, Wang D. Effects of TRAP-1-like protein (TLP) gene on collagen synthesis induced by TGF-β/Smad signaling in humandermal fibroblasts, PLoS One,2013,8(2):e55899.
6. Gu H, Xiong Z, Xu J, Li G, Wang C. Clinical and anatomical study of the distally based lesser saphenous veno-lateral sural neurocutaneous flap for lower extremity coverage, J Orthop Sci, 2013,18(5):740-748. (corresponding author)
7. Gong L, Wang C, Sun Q, Li G, Wang D. Effects of human adipose derived stem cells on the viability of rabbit random pattern flaps, Cytotherapy, 2